The Lattice Boltzmann method and computational analysis of bone dynamics-I

Introduction Organic tissues are composed of the cells and the extracellular milieu. The external environmental stimuli may induce several cellular activities inside the tissue which in turn can vary tissue matrix. Such stimuli can be mechanical, hormonal, chemical or electrical etc. In the case of mechanical stimuli, the cells within the subjected tissue undergo a few aspects of the mechanical stimulus, and decide to alter the tissue matrix in a pertinent manner depending upon the aptness of stimulus. The vertebrate skeleton plays a vital part in supplying mechanical support. Bone is a mineralized tissue and such mineralization is compulsory for its composition. Bone mineralization consists of a well organized practice of producing calcium phosphate by bone forming cells and put down in specific quantities inside the stringy matrix of bone. Bone is normally comprised of elastic collagen fiber besieged by firm hydroxyapatite mineral. A skeletal system is structurally strengthened by the noteworthy contribution of two main classes of bone tissue, called cancellous (trabecular or spongy) and cortical bone (haversian or compact). Cortical Abstract